Summary | Mutation origin | Mutation description | Expression | Phenotypes | Find Mice (IMSR) | Notes | References

Symbol:	Slc18a1tm1Dgen
Name:	solute carrier family 18 (vesicular monoamine), member 1; targeted mutation 1, Deltagen
MGI ID:	MGI:3663332
Gene:	Slc18a1  Location: Chr8:69490363-69541887 bp, - strand  Genetic Position: Chr8, 33.88 cM
Alliance:	Slc18a1tm1Dgen page

Mutant Cell Line:	7556
Germline Transmission:	Earliest citation of germline transmission: J:101679
Parent Cell Line:	E14 (ES Cell)
Strain of Origin:	129P2/OlaHsd
Project Collection:	Deltagen

Allele Type:    Targeted (Null/knockout, Reporter) Mutation:    Insertion   Mutation details: A LacZ-neomycin cassette was inserted into the gene so that the endogenous gene promoter drives expression of beta-galactosidase. Gene expression analysis confirmed the absence of expression in frontal cortex, striatum, hippocampus and adrenal gland. LacZ expression was detected in kidney, urinary bladder, adrenal glands, testis, prostate gland, and cervix. (J:101679, J:194189)

View phenotypes and curated references for all genotypes (concatenated display).

In Mice Carrying this Mutation:

37 assay results

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Slc18a1 Mutation:	22 strains or lines available

Original:	J:101679 Deltagen Inc, NIH initiative supporting placement of Deltagen, Inc. mice into public repositories. MGI Direct Data Submission. 2005;
All:	3 reference(s)