Ext1Gt(LST064)Byg
Gene trapped Allele Detail
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| Symbol: |
Ext1Gt(LST064)Byg |
| Name: |
exostosin glycosyltransferase 1; gene trap LST064, BayGenomics |
| MGI ID: |
MGI:2156190 |
| Synonyms: |
Ext1Gt(pGT1.8TM)64Wcs, Ext1Gt(pGT2TMpfs)064Wcs |
| Gene: |
Ext1 Location: Chr15:52931657-53209579 bp, - strand Genetic Position: Chr15, 20.0 cM
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| Alliance: |
Ext1Gt(LST064)Byg page
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| Mutant Cell Line: |
LST064 |
| Germline Transmission: |
Earliest citation of germline transmission:
J:70273
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| Parent Cell Line: |
E14 (ES Cell)
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| Strain of Origin: |
129P2/OlaHsd
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| Allele Type: |
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Gene trapped (Null/knockout, Reporter) |
| Mutation: |
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Insertion of gene trap vector
Vector: pGT2TMpfs
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Mutation details: The gene trap was inserted between exons 1 and 2, resulting in a fusion transcript of exon 1 fused to the gene trap vector sequence. The vector, pGT2TMpfs, contained part of En2, the transmembrane domain of CD4, Beta-geo, IRES, PLAP and pA elements. Northern blot against a cDNA probe for the 3' end of Ext1 showed no 3' mRNA present in mutants. This allele is reported to be a hypomorph (J:92212).
(J:91757)
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| Inheritance: |
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Recessive |
| Sequence Tags: |
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Sequence tag details (1 tag)
| Tag ID |
GenBank ID |
Method |
Tag Location (trapped strand)* |
Select |
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| Genome Context: |
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Genome Browser view of this mutation
15 gene trap insertions have trapped this gene
View all gene trap sequence tags in this region
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View phenotypes and curated references for all genotypes (concatenated display).
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| Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
| Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
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| Carrying any Ext1 Mutation: |
63 strains or lines available
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| Original: |
J:70273 Mitchell KJ, et al., Functional analysis of secreted and transmembrane proteins critical to mouse development. Nat Genet. 2001 Jul;28(3):241-9 |
| All: |
8 reference(s) |
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Analysis Tools
