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Htr2atm2Grch
Targeted Allele Detail
Summary
Symbol: Htr2atm2Grch
Name: 5-hydroxytryptamine (serotonin) receptor 2A; targeted mutation 2, Jay A Gingrich
MGI ID: MGI:3653427
Synonyms: htr2anr
Gene: Htr2a  Location: Chr14:74878314-74944299 bp, + strand  Genetic Position: Chr14, 39.37 cM
Alliance: Htr2atm2Grch page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:110958
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  129S6/SvEvTac
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutation:    Insertion
    A neomycin resistance gene-stop cassette was inserted into the 5' UTR to block transcription. (J:110958)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Htr2a Mutation:  42 strains or lines available
References
Original:  J:110958 Weisstaub NV, et al., Cortical 5-HT2A receptor signaling modulates anxiety-like behaviors in mice. Science. 2006 Jul 28;313(5786):536-40
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/09/2024
MGI 6.23
The Jackson Laboratory