Summary | Mutation origin | Mutation description | Expression | Phenotypes | Find Mice (IMSR) | References

Symbol:	Gja1tm1.1Gfi
Name:	gap junction protein, alpha 1; targeted mutation 1.1, Glenn I Fishman
MGI ID:	MGI:3652926
Synonyms:	Cx43-, Cx43fo
Gene:	Gja1  Location: Chr10:56253297-56266519 bp, + strand  Genetic Position: Chr10, 28.64 cM
Alliance:	Gja1tm1.1Gfi page

Germline Transmission:	Earliest citation of germline transmission: J:108525
Parent Cell Line:	Not Specified (ES Cell)
Strain of Origin:	Not Specified

Allele Type:    Targeted (Null/knockout) Mutation:    Intragenic deletion     The floxed exon 2 from Gja1tm1Gfi was removed via homologous recombination. (J:108525)

View phenotypes and curated references for all genotypes (concatenated display).

In Structures Affected by this Mutation:

3 anatomical structure(s)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Gja1 Mutation:	59 strains or lines available

Original:	J:108525 Liu S, et al., Distinct cardiac malformations caused by absence of connexin 43 in the neural crest and in the non-crest neural tube. Development. 2006 May;133(10):2063-73
All:	2 reference(s)