Summary | Mutation origin | Mutation description | Expression | Phenotypes | Find Mice (IMSR) | References

Symbol:	Rp1tm1Eap
Name:	retinitis pigmentosa 1 (human); targeted mutation 1, Eric A Pierce
MGI ID:	MGI:3652902
Synonyms:	Rp1btm1Eap, Rp1myc, Rp1-myc
Gene:	Rp1  Location: Chr1:4185896-4479508 bp, - strand  Genetic Position: Chr1, 1.65 cM
Alliance:	Rp1tm1Eap page

Germline Transmission:	Earliest citation of germline transmission: J:85754
Parent Cell Line:	TL1/TL-1 (ES Cell)
Strain of Origin:	129S6/SvEvTac

Allele Type:    Targeted (Null/knockout) Mutation:    Insertion   Mutation details: A targeting vector was designed to truncate the coding sequence after codon 662 in exon 4. A 10 amino acid myc tag was incorporated at the 3' end of the truncated exon 4. (J:85754)

View phenotypes and curated references for all genotypes (concatenated display).

In Structures Affected by this Mutation:

1 anatomical structure(s)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Rp1 Mutation:	121 strains or lines available

Original:	J:85754 Liu Q, et al., RP1 is required for the correct stacking of outer segment discs. Invest Ophthalmol Vis Sci. 2003 Oct;44(10):4171-83
All:	4 reference(s)