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Usf1tm1Svl
Targeted Allele Detail
Summary
Symbol: Usf1tm1Svl
Name: upstream transcription factor 1; targeted mutation 1, Sophie Vaulont
MGI ID: MGI:3640336
Synonyms: USF1-
Gene: Usf1  Location: Chr1:171238875-171246327 bp, + strand  Genetic Position: Chr1, 79.4 cM, cytoband H
Alliance: Usf1tm1Svl page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:49175
Parent Cell Line:  D3 (ES Cell)
Strain of Origin:  129S2/SvPas
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
 
Mutation detailsA targeting vector was designed to insert an IRES-Betageo into exon 4, replacing exons 5 through 9. Western blot failed to detect protein in mutants. (J:49175)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Usf1 Mutation:  81 strains or lines available
References
Original:  J:49175 Vallet VS, et al., Differential roles of upstream stimulatory factors 1 and 2 in the transcriptional response of liver genes to glucose. J Biol Chem. 1998 Aug 7;273(32):20175-9
All:  2 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/16/2024
MGI 6.23
The Jackson Laboratory