Summary | Mutation origin | Mutation description | Phenotypes | Find Mice (IMSR) | References

Symbol:	Ryr2tm1Hta
Name:	ryanodine receptor 2, cardiac; targeted mutation 1, Hiroshi Takeshima
MGI ID:	MGI:3640297
Synonyms:	Crrm1, Ryr2flox
Gene:	Ryr2  Location: Chr13:11567988-12121831 bp, - strand  Genetic Position: Chr13, 4.38 cM, cytoband A1-A2
Alliance:	Ryr2tm1Hta page

Germline Transmission:	Earliest citation of germline transmission: J:48277
Parent Cell Line:	J1 (ES Cell)
Strain of Origin:	129S4/SvJae

Allele Type:    Targeted (Conditional ready, No functional change) Mutation:    Insertion   Mutation details: A targeting vector was designed to insert loxP sequences flanking exon 1. A GFP-neo was included in the vector. This mutation is thought to be silent. (J:48277)

View phenotypes and curated references for all genotypes (concatenated display).

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Ryr2 Mutation:	325 strains or lines available

Original:	J:48277 Takeshima H, et al., Embryonic lethality and abnormal cardiac myocytes in mice lacking ryanodine receptor type 2. EMBO J. 1998 Jun 15;17(12):3309-16
All:	3 reference(s)