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Hsf1Gt(pU18)54Imeg
Gene trapped Allele Detail
Nomenclature
Symbol: Hsf1Gt(pU18)54Imeg
Name: heat shock factor 1; gene trap 54, Institute of Molecular Embryology and Genetics
MGI ID: MGI:3639095
Synonyms: GtAyu18-54, Gt(Ayu18)54Imeg
Gene: Hsf1  Location: Chr15:76361562-76385355 bp, + strand  Genetic Position: Chr15, 35.95 cM
Mutation
origin
Mutant Cell Line:  Ayu18-54
Germline Transmission:  Earliest citation of germline transmission: J:109358
Parent Cell Line:  KTPU10 (ES Cell)
Strain of Origin:  (C57BL/6NCrlj x CBA/JNCrlj)F1
Mutation
description
Allele Type:    Gene trapped
Mutation:    Insertion of gene trap vector     Vector: pU-18
 
Mutation detailsThe randomly integrating (within a gene) gene trap vector pU18 contains 1.8 kb of intron 1 and part of exon 2, including the splice acceptor, from the mouse engrailed 2 gene (En2) followed by an internal ribosome entry site (IRES) and the Betageo beta-galactosidase/neomycin resistance fusion gene with a mammalian polyadenylation signal. Three stop codons occur in the exon sequence upstream of and in frame with the Betageo translation initiation codon. Mutant and wild-type loxP sites used for 5' RACE analysis and for in vitro exchange of other sequences for Betageo are present. (J:109358, J:110088)
Inheritance:    Not Specified
Sequence Tags: 
Sequence tag details (1 tag)
Genome Context: 
Genome Browser view of this mutation
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Hsf1 Mutation:  16 strains or lines available
Notes
Integration site GenBank ID: AB212666
References
Original:  J:109358 Database for Exchangeable Gene Trap Clones, Information obtained from the Database for Exchangeable Gene Trap Clones (EGTC), an official database of the Gene Trap Project of the Institute of Molecular Embryology and Genetics and the Institute of Resource Development and Analysis, Kumamoto University, Japan. Unpublished. 2006;
All:  3 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
10/12/2021
MGI 6.17
The Jackson Laboratory