Summary | Mutation origin | Mutation description | Expression | Phenotypes | Find Mice (IMSR) | References

Symbol:	Slc6a4tm1Grch
Name:	solute carrier family 6 (neurotransmitter transporter, serotonin), member 4; targeted mutation 1, Jay A Gingrich
MGI ID:	MGI:3629666
Synonyms:	5-htt-
Gene:	Slc6a4  Location: Chr11:76889429-76923166 bp, + strand  Genetic Position: Chr11, 46.18 cM
Alliance:	Slc6a4tm1Grch page

Germline Transmission:	Earliest citation of germline transmission: J:109542
Parent Cell Line:	Not Specified (ES Cell)
Strain of Origin:	129S6/SvEvTac

Allele Type:    Targeted (Null/knockout) Mutations:    Insertion, Intragenic deletion   Mutation details: The first coding exon of the transporter-coding region was partially deleted and replaced with a neomycin resistance cassette. (J:109542)

View phenotypes and curated references for all genotypes (concatenated display).

In Mice Carrying this Mutation:

1 RNA-Seq or microarray experiment(s)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Slc6a4 Mutation:	51 strains or lines available

Original:	J:109542 Lira A, et al., Altered depression-related behaviors and functional changes in the dorsal raphe nucleus of serotonin transporter-deficient mice. Biol Psychiatry. 2003 Nov 15;54(10):960-71
All:	4 reference(s)