Summary | Mutation origin | Mutation description | Expression | Phenotypes | Find Mice (IMSR) | References

Symbol:	Sox2tm3Lpev
Name:	SRY (sex determining region Y)-box 2; targeted mutation 3, Larysa H Pevny
MGI ID:	MGI:3625177
Synonyms:	Sox2LP
Gene:	Sox2  Location: Chr3:34704554-34706610 bp, + strand  Genetic Position: Chr3, 16.93 cM, cytoband A2-B
Alliance:	Sox2tm3Lpev page

Germline Transmission:	Earliest citation of germline transmission: J:108452
Parent Cell Line:	CCE/EK.CCE (ES Cell)
Strain of Origin:	129S/SvEv-Gpi1c

Allele Type:    Targeted (Hypomorph) Mutation:    Insertion   Mutation details: A targeting vector inserted partially such that a neo and loxP site were inserted 5' to the locus. This allele is a hypomorph. (J:108452)

View phenotypes and curated references for all genotypes (concatenated display).

In Mice Carrying this Mutation:	18 assay results
In Structures Affected by this Mutation:	11 anatomical structure(s)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Sox2 Mutation:	56 strains or lines available

Original:	J:108452 Taranova OV, et al., SOX2 is a dose-dependent regulator of retinal neural progenitor competence. Genes Dev. 2006 May 1;20(9):1187-202
All:	6 reference(s)