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Sox2tm2.1Lpev
Targeted Allele Detail
Summary
Symbol: Sox2tm2.1Lpev
Name: SRY (sex determining region Y)-box 2; targeted mutation 2.1, Larysa H Pevny
MGI ID: MGI:3625176
Synonyms: Sox2deltaCOND
Gene: Sox2  Location: Chr3:34704554-34706610 bp, + strand  Genetic Position: Chr3, 16.93 cM, cytoband A2-B
Alliance: Sox2tm2.1Lpev page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:108452
Parent Cell Line:  CCE/EK.CCE (ES Cell)
Strain of Origin:  129S/SvEv-Gpi1c
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutation:    Intragenic deletion
 
Mutation detailsCre mediated recombination was used to remove the floxed sequence, including the promoter and coding sequence. (J:108452)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Expression
In Structures Affected by this Mutation: 1 anatomical structure(s)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Sox2 Mutation:  56 strains or lines available
References
Original:  J:108452 Taranova OV, et al., SOX2 is a dose-dependent regulator of retinal neural progenitor competence. Genes Dev. 2006 May 1;20(9):1187-202
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/19/2024
MGI 6.23
The Jackson Laboratory