Summary | Mutation origin | Mutation description | Find Mice (IMSR) | References

Symbol:	Dcxtm1.1Ffr
Name:	doublecortin; targeted mutation 1.1, Fiona Francis
MGI ID:	MGI:3624536
Gene:	Dcx  Location: ChrX:142638838-142716307 bp, - strand  Genetic Position: ChrX, 64.89 cM
Alliance:	Dcxtm1.1Ffr page

Germline Transmission:	Earliest citation of germline transmission: J:108229
Parent Cell Line:	Not Specified (ES Cell)
Strain of Origin:	129S2/SvPas

Allele Type:    Targeted (Conditional ready, No functional change) Mutation:    Insertion   Mutation details: LoxP sites were inserted to flank exon 3 and a PGK-neo cassette. The neo was excised following cre-mediated recombination. (J:108229)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 2 strains available      Cell Lines: 0 lines available
Carrying any Dcx Mutation:	18 strains or lines available

Original:	J:108229 Kappeler C, et al., Branching and nucleokinesis defects in migrating interneurons derived from doublecortin knockout mice. Hum Mol Genet. 2006 May 1;15(9):1387-400
All:	2 reference(s)