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Rag2tm2Fwa
Targeted Allele Detail
Summary
Symbol: Rag2tm2Fwa
Name: recombination activating gene 2; targeted mutation 2, Frederick W Alt
MGI ID: MGI:3623131
Synonyms: Rag2GFP
Gene: Rag2  Location: Chr2:101455063-101462874 bp, + strand  Genetic Position: Chr2, 53.87 cM
Alliance: Rag2tm2Fwa page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:57268
Parent Cell Line:  TC1/TC-1 (ES Cell)
Strain of Origin:  129S6/SvEvTac
Mutation
description
Allele Type:    Targeted (Null/knockout, Reporter)
Mutation:    Insertion
 
Mutation detailsA functional Rag2-GFP fusion cDNA replaced the endogenous coding sequence. A floxed neo was included in the vector and later removed via cre-mediated recombination. (J:57268)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Rag2 Mutation:  117 strains or lines available
References
Original:  J:57268 Monroe RJ, et al., RAG2:GFP knockin mice reveal novel aspects of RAG2 expression in primary and peripheral lymphoid tissues. Immunity. 1999 Aug;11(2):201-12
All:  5 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/16/2024
MGI 6.23
The Jackson Laboratory