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Rr320tm4.1Mkg
Targeted Allele Detail
Summary
Symbol: Rr320tm4.1Mkg
Name: regulatory region 320; targeted mutation 4.1, Mark Groudine
MGI ID: MGI:3621029
Synonyms: delta1, Hbb-artm4.1Mkg
Gene: Rr320  Location: Chr7:103501973-103526752 bp, + strand  Genetic Position: Chr7, Syntenic
Alliance: Rr320tm4.1Mkg page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:106655
Parent Cell Line:  AK7 (ES Cell)
Strain of Origin:  129S4/SvJaeSor
Mutation
description
Allele Type:    Targeted (Modified regulatory region, Null/knockout)
Mutation:    Intragenic deletion
 
Mutation detailsThe loxP site flanked neomycin resistance gene cassette was removed via cre-mediated excision from Rr320tm4Mkg, leaving the deletion of 5'HS1 encoded by nucleotides -4675 to -6999 relative to the Ey cap site. (J:106655)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Rr320 Mutation:  0 strains or lines available
References
Original:  J:106655 Bender MA, et al., Targeted deletion of 5'HS1 and 5'HS4 of the beta-globin locus control region reveals additive activity of the DNaseI hypersensitive sites. Blood. 2001 Oct 1;98(7):2022-7
All:  2 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/16/2024
MGI 6.23
The Jackson Laboratory