Summary | Mutation origin | Mutation description | Expression | Phenotypes | Find Mice (IMSR) | References

Symbol:	Tbx1tm2Bem
Name:	T-box 1; targeted mutation 2, Bernice E Morrow
MGI ID:	MGI:3619531
Gene:	Tbx1  Location: Chr16:18399729-18409412 bp, - strand  Genetic Position: Chr16, Syntenic
Alliance:	Tbx1tm2Bem page

Germline Transmission:	Earliest citation of germline transmission: J:105980
Parent Cell Line:	Not Specified (ES Cell)
Strain of Origin:	Not Specified

Allele Type:    Targeted (Conditional ready, No functional change) Mutation:    Insertion   Mutation details: A Hygromycin-resistance cassette flanked by loxP sites was inserted between exons 3 and 4 along with a single loxP site between exons 1 and 2. The ATG is in exon 2. (J:105980)

View phenotypes and curated references for all genotypes (concatenated display).

In Structures Affected by this Mutation:

1 anatomical structure(s)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Tbx1 Mutation:	34 strains or lines available

Original:	J:105980 Arnold JS, et al., Inactivation of Tbx1 in the pharyngeal endoderm results in 22q11DS malformations. Development. 2006 Mar;133(5):977-87
All:	2 reference(s)