Summary | Mutation origin | Mutation description | Expression | Phenotypes | Disease models | Find Mice (IMSR) | References

Symbol:	Tbx1tm2.2Bem
Name:	T-box 1; targeted mutation 2.2, Bernice E Morrow
MGI ID:	MGI:3619150
Synonyms:	Tbx1-, Tbx1tm1.2Bem
Gene:	Tbx1  Location: Chr16:18399729-18409412 bp, - strand  Genetic Position: Chr16, Syntenic
Alliance:	Tbx1tm2.2Bem page

Germline Transmission:	Earliest citation of germline transmission: J:105980
Parent Cell Line:	WW6 (ES Cell)
Strain of Origin:	STOCK 129/Sv and C57BL/6J and SJL

Allele Type:    Targeted (Null/knockout) Mutation:    Intragenic deletion     Exons 2 and 3 were removed via cre-mediated excision. The ATG is in exon 2. (J:105980)

View phenotypes and curated references for all genotypes (concatenated display).

In Mice Carrying this Mutation:	83 assay results 3 RNA-Seq or microarray experiment(s)
In Structures Affected by this Mutation:	30 anatomical structure(s)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Tbx1 Mutation:	34 strains or lines available

Original:	J:105980 Arnold JS, et al., Inactivation of Tbx1 in the pharyngeal endoderm results in 22q11DS malformations. Development. 2006 Mar;133(5):977-87
All:	10 reference(s)