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H2-D1bm13
Spontaneous Allele Detail
Summary
Symbol: H2-D1bm13
Name: histocompatibility 2, D region locus 1; b haplotype mutation 13
MGI ID: MGI:3618116
Synonyms: H-2bn
Gene: H2-D1  Location: Chr17:35482070-35486473 bp, + strand  Genetic Position: Chr17, 18.61 cM
Alliance: H2-D1bm13 page
Mutation
origin
Strain of Origin:  (C57BL/6ByKh x BALB/cByKh)F1
Mutation
description
Allele Type:    Spontaneous
Mutation:    Nucleotide substitutions
 
Mutation detailsThe bm13 mutation consists of four nucleotide changes that result in amino acid changes in codons 114 (leucine to glycine), 116 (phenylalanine to tyrosine) and 119 (glutamate to aspartate). A mutation in codon 118 is silent. The mutation is thought to have arisen by a gene conversion event with the H-2Kb acting as the donor locus. (J:106337)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any H2-D1 Mutation:  45 strains or lines available
References
Original:  J:106349 Melvold RW, et al., Eight new histocompatibility mutations associated with the H-2 complex. Immunogenetics. 1976;3:185-191
All:  16 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/09/2024
MGI 6.23
The Jackson Laboratory