Summary | Mutation origin | Mutation description | Expression | Phenotypes | Find Mice (IMSR) | References

Symbol:	Snai1tm2Grid
Name:	snail family zinc finger 1; targeted mutation 1, Tom Gridley
MGI ID:	MGI:3617387
Synonyms:	Snai1flox
Gene:	Snai1  Location: Chr2:167380115-167384734 bp, + strand  Genetic Position: Chr2, 87.33 cM
Alliance:	Snai1tm2Grid page

Germline Transmission:	Earliest citation of germline transmission: J:105294
Parent Cell Line:	CJ7 (ES Cell)
Strain of Origin:	129S1/Sv-Oca2+ Tyr+ Kitl+

Allele Type:    Targeted (Conditional ready, No functional change) Mutation:    Insertion   Mutation details: LoxP sites were inserted to flank promoter sequences, exons 1 and 2. The frt flanked neo cassette was removed by flp mediated recombination. Deletion of this sequence would remove the start codon, the 5' SNAG repression domain and the first three zinc finger DNA binding domains of the protein. (J:105294)

View phenotypes and curated references for all genotypes (concatenated display).

In Mice Carrying this Mutation:	86 assay results
In Structures Affected by this Mutation:	3 anatomical structure(s)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Snai1 Mutation:	9 strains or lines available

Original:	J:105294 Murray SA, et al., Generation of a Snail1 (Snai1) conditional null allele. Genesis. 2006 Jan;44(1):7-11
All:	19 reference(s)