Summary | Mutation origin | Mutation description | Expression | Phenotypes | Disease models | Find Mice (IMSR) | References

Symbol:	Fscn2tm2Sykk
Name:	fascin actin-bundling protein 2; targeted mutation 2, Shinji Yokokura
MGI ID:	MGI:3612338
Synonyms:	Fscn2g neo-
Gene:	Fscn2  Location: Chr11:120252360-120258994 bp, + strand  Genetic Position: Chr11, 84.08 cM
Alliance:	Fscn2tm2Sykk page

Germline Transmission:	Earliest citation of germline transmission: J:103713
Parent Cell Line:	J1 (ES Cell)
Strain of Origin:	129S4/SvJae

Allele Type:    Targeted (Null/knockout) Mutations:    Insertion, Intragenic deletion   Mutation details: Exon 1 was replaced by GFP. Cre mediated recombination removed a floxed neomycin selection cassette. Fluorescence was detected in the photoreceptors. (J:103713)

View phenotypes and curated references for all genotypes (concatenated display).

In Structures Affected by this Mutation:

3 anatomical structure(s)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Fscn2 Mutation:	37 strains or lines available

Original:	J:103713 Yokokura S, et al., Targeted disruption of FSCN2 gene induces retinopathy in mice. Invest Ophthalmol Vis Sci. 2005 Aug;46(8):2905-15
All:	2 reference(s)