Summary | Mutation origin | Mutation description | Phenotypes | Find Mice (IMSR) | References

Symbol:	Gria3tm1.1Rsp
Name:	glutamate receptor, ionotropic, AMPA3 (alpha 3); targeted mutation 1.1, Rolf Sprengel
MGI ID:	MGI:3611329
Synonyms:	GluR3-, GluR-C1lox, GRIA3fl
Gene:	Gria3  Location: ChrX:40489731-40767478 bp, + strand  Genetic Position: ChrX, 23.19 cM
Alliance:	Gria3tm1.1Rsp page

Germline Transmission:	Earliest citation of germline transmission: J:104146
Parent Cell Line:	R1 (ES Cell)
Strain of Origin:	(129X1/SvJ x 129S1/Sv)F1-Kitl+

Allele Type:    Targeted (Null/knockout) Mutation:    Intragenic deletion   Mutation details: This allele was derived from Gria3tm1Rsp by crossing mice carrying that allele with Tg(CMV-cre)1Cgn. This resulted in the excision of both the neomycin cassette and exon 11. Absence of gene product was confirmed by Western blot analysis of brain extracts. (J:104146)

View phenotypes and curated references for all genotypes (concatenated display).

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Gria3 Mutation:	10 strains or lines available

Original:	J:104146 Sanchis-Segura C, et al., Involvement of the AMPA receptor GluR-C subunit in alcohol-seeking behavior and relapse. J Neurosci. 2006 Jan 25;26(4):1231-8
All:	8 reference(s)