Summary | Mutation origin | Mutation description | Expression | Phenotypes | Find Mice (IMSR) | References

Symbol:	Ihhtm1Blan
Name:	Indian hedgehog; targeted mutation 1, Beate Lanske
MGI ID:	MGI:3609381
Synonyms:	Ihhfl
Gene:	Ihh  Location: Chr1:74984474-74990831 bp, - strand  Genetic Position: Chr1, 38.55 cM
Alliance:	Ihhtm1Blan page

Germline Transmission:	Earliest citation of germline transmission: J:102870
Parent Cell Line:	J1 (ES Cell)
Strain of Origin:	129S4/SvJae

Allele Type:    Targeted (Conditional ready, No functional change) Mutation:    Insertion   Mutation details: A targeting vector was designed to insert a loxP site upstream of exon 1, followed by a frt-flanked neomycin resistance (neo) cassette, and a second loxP site downstream of exon 1. Flp-mediated recombination removed the neo cassette. (J:102870)

View phenotypes and curated references for all genotypes (concatenated display).

In Mice Carrying this Mutation:	1 RNA-Seq or microarray experiment(s)
In Structures Affected by this Mutation:	10 anatomical structure(s)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Ihh Mutation:	22 strains or lines available

Original:	J:102870 Razzaque MS, et al., Conditional deletion of Indian hedgehog from collagen type 2alpha1-expressing cells results in abnormal endochondral bone formation. J Pathol. 2005 Dec;207(4):453-61
All:	24 reference(s)