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Gli3Xt
Spontaneous Allele Detail
Summary
Symbol: Gli3Xt
Name: GLI-Kruppel family member GLI3; extra toes
MGI ID: MGI:1856275
Synonyms: Gli3-, XtH
Gene: Gli3  Location: Chr13:15638308-15904611 bp, + strand  Genetic Position: Chr13, 5.43 cM, cytoband A2
Alliance: Gli3Xt page
Mutation
origin
Strain of Origin:  CBA/H x (C3H/HeH x 101/H)F1
Mutation
description
Allele Type:    Spontaneous
Mutation:    Deletion
  Gli3Xt involves 1 genes/genome features (Gli3) View all
 
Mutation detailsSouthern Blot analysis of genomic DNA from +/+, Xt/+ and Xt/Xt mice showed that at least part of the Gli3 gene (cDNA homologous with a 5' part of the human GLI3 gene) is deleted in the Gli3Xt allele. (J:1718, J:3333, J:11318)
Inheritance:    Semidominant
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Expression
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Gli3 Mutation:  80 strains or lines available
References
Original:  J:12947 Lyon MF, et al., The overall rates of dominant and recessive lethal and visible mutation induced by spermatogonial X-irradiation of mice. Genet Res. 1964;5(3):448-467
All:  54 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/16/2024
MGI 6.23
The Jackson Laboratory