Summary | Mutation origin | Mutation description | Expression | Phenotypes | Find Mice (IMSR) | Notes | References

Symbol:	Ppardtm1Dgen
Name:	peroxisome proliferator activator receptor delta; targeted mutation 1, Deltagen
MGI ID:	MGI:3604590
Gene:	Ppard  Location: Chr17:28451715-28520446 bp, + strand  Genetic Position: Chr17, 14.64 cM
Alliance:	Ppardtm1Dgen page

Mutant Cell Line:	1481
Germline Transmission:	Earliest citation of germline transmission: J:101679
Parent Cell Line:	E14 (ES Cell)
Strain of Origin:	129P2/OlaHsd
Project Collection:	Deltagen

Allele Type:    Targeted (Null/knockout, Reporter) Mutation:    Insertion   Mutation details: A bacterial lacZ gene was inserted into the gene such that the endogenous gene promoter drives expression of beta-galactosidase. RT-PCR analysis detects a gene transcript in all tissues examined; beta-galactosidase expression is detectable in brain, spinal cord, eye, pancreas, kidneys, trachea, larynx, esophagus, pituitary gland, parathyroid gland, tongue, skin, male and female reproductive systems.

View phenotypes and curated references for all genotypes (concatenated display).

In Mice Carrying this Mutation:

112 assay results

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Ppard Mutation:	68 strains or lines available

Original:	J:101679 Deltagen Inc, NIH initiative supporting placement of Deltagen, Inc. mice into public repositories. MGI Direct Data Submission. 2005;
All:	1 reference(s)