Summary | Mutation origin | Mutation description | Expression | Phenotypes | Find Mice (IMSR) | Notes | References

Symbol:	Slc7a8tm1Dgen
Name:	solute carrier family 7 (cationic amino acid transporter, y+ system), member 8; targeted mutation 1, Deltagen
MGI ID:	MGI:3604565
Gene:	Slc7a8  Location: Chr14:54959672-55019343 bp, - strand  Genetic Position: Chr14, 27.91 cM
Alliance:	Slc7a8tm1Dgen page

Mutant Cell Line:	6136
Germline Transmission:	Earliest citation of germline transmission: J:101679
Parent Cell Line:	E14 (ES Cell)
Strain of Origin:	129P2/OlaHsd
Project Collection:	Deltagen

Allele Type:    Targeted (Null/knockout, Reporter) Mutation:    Insertion   Mutation details: A bacterial lacZ gene was inserted into the gene such that the endogenous gene promoter drives expression of beta-galactosidase. While high levels of RNA transcripts are detected in pancreas and kidney, moderate levels are found in many of the tissues tested. Beta-galactosidase expression from this allele is detectable in several organs examined, with most striking expression in brain, eyes, pancreas, kidney and testis. (J:101679)

View phenotypes and curated references for all genotypes (concatenated display).

In Mice Carrying this Mutation:

54 assay results

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Slc7a8 Mutation:	34 strains or lines available

Original:	J:101679 Deltagen Inc, NIH initiative supporting placement of Deltagen, Inc. mice into public repositories. MGI Direct Data Submission. 2005;
All:	2 reference(s)