Summary | Mutation origin | Mutation description | Expression | Phenotypes | Find Mice (IMSR) | Notes | References

Symbol:	Cacna2d3tm1Dgen
Name:	calcium channel, voltage-dependent, alpha2/delta subunit 3; targeted mutation 1, Deltagen
MGI ID:	MGI:3604520
Gene:	Cacna2d3  Location: Chr14:28626900-29443821 bp, - strand  Genetic Position: Chr14, 16.8 cM, cytoband B
Alliance:	Cacna2d3tm1Dgen page

Mutant Cell Line:	1924
Germline Transmission:	Earliest citation of germline transmission: J:101679
Parent Cell Line:	E14 (ES Cell)
Strain of Origin:	129P2/OlaHsd
Project Collection:	Deltagen

Allele Type:    Targeted (Null/knockout, Reporter) Mutation:    Insertion   Mutation details: A bacterial lacZ gene was inserted into the gene such that the endogenous gene promoter drives expression of beta-galactosidase. RNA transcripts are detectable in brain, cortex, subcortical region, cerebellum, brainstem, olfactory bulb, spinal cord, eye, heart, lung, spleen, lymph nodes, skin, urinary bladder, pituitary gland, adrenal gland, skeletal muscle, tongue, stomach, small intestine, large intestine, cecum, testis, epididymis, coagulating gland, prostate gland, ovary, uterus and white fat. LacZ (beta-galactosidase) expression is detectable in brain and testis.

View phenotypes and curated references for all genotypes (concatenated display).

In Mice Carrying this Mutation:

54 assay results

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Cacna2d3 Mutation:	64 strains or lines available

Original:	J:101679 Deltagen Inc, NIH initiative supporting placement of Deltagen, Inc. mice into public repositories. MGI Direct Data Submission. 2005;
All:	9 reference(s)