Summary | Mutation origin | Mutation description | Expression | Phenotypes | Find Mice (IMSR) | Notes | References

Symbol:	Adcy3tm1Dgen
Name:	adenylate cyclase 3; targeted mutation 1, Deltagen
MGI ID:	MGI:3604495
Gene:	Adcy3  Location: Chr12:4183397-4263525 bp, + strand  Genetic Position: Chr12, 1.99 cM, cytoband A-B
Alliance:	Adcy3tm1Dgen page

Mutant Cell Line:	4446
Germline Transmission:	Earliest citation of germline transmission: J:101679
Parent Cell Line:	E14 (ES Cell)
Strain of Origin:	129P2/OlaHsd
Project Collection:	Deltagen

Allele Type:    Targeted (Null/knockout, Reporter) Mutation:    Insertion   Mutation details: A bacterial lacZ gene was inserted into the gene such that the endogenous gene promoter drives expression of beta-galactosidase. RNA transcripts are detectable in all tissues analyzed. LacZ (beta-galactosidase) expression is detectable in brain, Harderian glands, aorta, heart, lung, kidney, urinary bladder, salivary glands, tongue, external ear, male and female reproductive systems. In many of the tissues with detectable expression, lacZ expression is detectable in blood vessels.

View phenotypes and curated references for all genotypes (concatenated display).

In Mice Carrying this Mutation:

66 assay results

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Adcy3 Mutation:	42 strains or lines available

Original:	J:101679 Deltagen Inc, NIH initiative supporting placement of Deltagen, Inc. mice into public repositories. MGI Direct Data Submission. 2005;
All:	5 reference(s)