Slc25a12Gt(OST123999)Lex
Gene trapped Allele Detail
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| Symbol: |
Slc25a12Gt(OST123999)Lex |
| Name: |
solute carrier family 25 (mitochondrial carrier, Aralar), member 12; gene trap OST123999, Lexicon Genetics |
| MGI ID: |
MGI:3603462 |
| Synonyms: |
Aralar-, Slc25a12Gt(neo)1Lex |
| Gene: |
Slc25a12 Location: Chr2:71104614-71198125 bp, - strand Genetic Position: Chr2, 42.38 cM
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| Alliance: |
Slc25a12Gt(OST123999)Lex page
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| Mutant Cell Line: |
OST123999 |
| Germline Transmission: |
Earliest citation of germline transmission:
J:101164
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| Parent Cell Line: |
Lex-1 (ES Cell)
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| Strain of Origin: |
129S5/SvEvBrd
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| Project Collection: |
Lexicon
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| Allele Type: |
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Gene trapped (Null/knockout, Reporter) |
| Mutation: |
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Insertion of gene trap vector
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Mutation details: A gene trap vector containing a splice acceptor site and a BTK-neo was inserted into intron 13. Northern blot detected a fusion transcript between the 5' endogenous locus and the neo. Western blot demonstrated lack of endogenous protein in mutants.
(J:101164)
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| Sequence Tags: |
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Sequence tag details (1 tag)
| Tag ID |
GenBank ID |
Method |
Tag Location (trapped strand)* |
Select |
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| Genome Context: |
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Genome Browser view of this mutation
80 gene trap insertions have trapped this gene
View all gene trap sequence tags in this region
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View phenotypes and curated references for all genotypes (concatenated display).
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| Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
| Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
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| Carrying any Slc25a12 Mutation: |
103 strains or lines available
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| Original: |
J:101164 Jalil MA, et al., Reduced N-acetylaspartate levels in mice lacking aralar, a brain- and muscle-type mitochondrial aspartate-glutamate carrier. J Biol Chem. 2005 Sep 2;280(35):31333-9 |
| All: |
14 reference(s) |
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Analysis Tools
