Summary | Mutation origin | Mutation description | Recombinase activity | Phenotypes | Find Mice (IMSR) | Notes | References

Symbol:	Prkcgtm1(cre)Zfc
Name:	protein kinase C, gamma; targeted mutation 1, Zhou-Feng Chen
MGI ID:	MGI:3603180
Synonyms:	PKCgamma-Cre
Gene:	Prkcg  Location: Chr7:3352038-3379615 bp, + strand  Genetic Position: Chr7, 1.93 cM
Alliance:	Prkcgtm1(cre)Zfc page

Germline Transmission:	Earliest citation of germline transmission: J:100950
Parent Cell Line:	Other (see notes) (ES Cell)
Strain of Origin:	129S7/SvEvBrd

Allele Type:    Targeted (Recombinase) Mutation:    Insertion   Prkcgtm1(cre)Zfc expression driven by 1 gene Knock-in expression driven by: Organism Driver Gene Note mouse Prkcg (MGI:97597)   Mutation details: Cre recombinase cDNA and a PGK-neo were inserted at the ATG to replace the first two coding exons. Immunohistochemical staining demonstrated cre-expressing cells with high density in the cerebral cortex, hippocampus, amgdala and thalamus and with low density in the olfactory system, septal region, basal ganglia, hypothalamus, brainstem and spinal cord. (J:100950)

Activity:	Tissue activity of this recombinase allele
Driver:	Prkcg (mouse) Summary of all recombinase alleles driven by Prkcg. Alliance mouse Prkcg gene page

View phenotypes and curated references for all genotypes (concatenated display).

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Prkcg Mutation:	42 strains or lines available

Original:	J:100950 Ding YQ, et al., Generation and characterization of the PKCgamma-Cre mouse line. Genesis. 2005 Sep;43(1):28-33
All:	4 reference(s)