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Targeted Allele Detail
Symbol: Sox15tm1Yam
Name: SRY (sex determining region Y)-box 15; targeted mutation 1, Shinya Yamanaka
MGI ID: MGI:3590592
Synonyms: Sox15-
Gene: Sox15  Location: Chr11:69655314-69656727 bp, + strand  Genetic Position: Chr11, 42.86 cM
Germline Transmission:  Earliest citation of germline transmission: J:100846
Parent Cell Line:  RF8 (ES Cell)
Strain of Origin:  129S4/SvJae
Allele Type:    Targeted (Null/knockout)
Mutation:    Insertion
Mutation detailsAn IRES-betageo was inserted into the first exon, upstream of the HMG domain. Absence of transcript was shown by Northern blot of mutant ES cells. (J:100846)
View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Sox15 Mutation:  14 strains or lines available
Original:  J:100846 Maruyama M, et al., Differential roles for Sox15 and Sox2 in transcriptional control in mouse embryonic stem cells. J Biol Chem. 2005 Jul 1;280(26):24371-9
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
MGI 6.14
The Jackson Laboratory