About   Help   FAQ
Sox15tm1Yam
Targeted Allele Detail
Nomenclature
Symbol: Sox15tm1Yam
Name: SRY (sex determining region Y)-box 15; targeted mutation 1, Shinya Yamanaka
MGI ID: MGI:3590592
Synonyms: Sox15-
Gene: Sox15  Location: Chr11:69655314-69656727 bp, + strand  Genetic Position: Chr11, 42.86 cM
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:100846
Parent Cell Line:  RF8 (ES Cell)
Strain of Origin:  129S4/SvJae
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutation:    Insertion
 
Mutation detailsAn IRES-betageo was inserted into the first exon, upstream of the HMG domain. Absence of transcript was shown by Northern blot of mutant ES cells. (J:100846)
Phenotypes
Loading...
View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Sox15 Mutation:  14 strains or lines available
References
Original:  J:100846 Maruyama M, et al., Differential roles for Sox15 and Sox2 in transcriptional control in mouse embryonic stem cells. J Biol Chem. 2005 Jul 1;280(26):24371-9
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support.
last database update
01/14/2020
MGI 6.14
The Jackson Laboratory