Summary | Mutation origin | Mutation description | Phenotypes | Find Mice (IMSR) | References

Symbol:	Gt(ROSA)26Sortm2(Wnt1/GFP)Amc
Name:	gene trap ROSA 26, Philippe Soriano; targeted mutation 2, Andrew P McMahon
MGI ID:	MGI:3589804
Synonyms:	ROSA-Wnt1
Gene:	Gt(ROSA)26Sor  Location: Chr6:113044389-113054205 bp, - strand  Genetic Position: Chr6, 52.73 cM
Alliance:	Gt(ROSA)26Sortm2(Wnt1/GFP)Amc page

Germline Transmission:	Earliest citation of germline transmission: J:100575
Parent Cell Line:	AV3 (ES Cell)
Strain of Origin:	129X1/SvJ

Allele Type:    Targeted (Conditional ready, Inserted expressed sequence, Reporter) Mutation:    Insertion   Gt(ROSA)26Sortm2(Wnt1/GFP)Amc expresses 1 gene Knock-in expresses: Organism Expressed Gene Note mouse Wnt1 (MGI:98953)   Mutation details: A full-length Wnt1-GFP construct was inserted into the locus downstream of a floxed triple polyA sequence. Upon cre expression, the cassette is removed and Wnt1-GFP is expressed. (J:100575)

View phenotypes and curated references for all genotypes (concatenated display).

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Gt(ROSA)26Sor Mutation:	942 strains or lines available

Original:	J:100575 Carroll TJ, et al., Wnt9b plays a central role in the regulation of mesenchymal to epithelial transitions underlying organogenesis of the mammalian urogenital system. Dev Cell. 2005 Aug;9(2):283-92
All:	8 reference(s)