Summary | Mutation origin | Mutation description | Phenotypes | Find Mice (IMSR) | References

Symbol:	Gria3tm2Rlh
Name:	glutamate receptor, ionotropic, AMPA3 (alpha 3); targeted mutation 2, Richard L Huganir
MGI ID:	MGI:3584157
Synonyms:	Glur3-
Gene:	Gria3  Location: ChrX:40489731-40767478 bp, + strand  Genetic Position: ChrX, 23.19 cM
Alliance:	Gria3tm2Rlh page

Germline Transmission:	Earliest citation of germline transmission: J:99813
Parent Cell Line:	R1 (ES Cell)
Strain of Origin:	(129X1/SvJ x 129S1/Sv)F1-Kitl+

Allele Type:    Targeted (Null/knockout) Mutation:    Insertion   Mutation details: A targeting vector was designed to insert a neomycin resistance cassette in the exon encoding transmembranes 1 and 2. Western blot of mutant brain samples confirmed absence of protein. (J:99813)

View phenotypes and curated references for all genotypes (concatenated display).

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Gria3 Mutation:	10 strains or lines available

Original:	J:99813 Gardner SM, et al., Calcium-permeable AMPA receptor plasticity is mediated by subunit-specific interactions with PICK1 and NSF. Neuron. 2005 Mar 24;45(6):903-15
All:	2 reference(s)