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Lmo2tm4Thr
Targeted Allele Detail
Summary
Symbol: Lmo2tm4Thr
Name: LIM domain only 2; targeted mutation 4, Terence H Rabbitts
MGI ID: MGI:3584123
Synonyms: Lmo2lacZ, Lmo2-lacZ
Gene: Lmo2  Location: Chr2:103788340-103812223 bp, + strand  Genetic Position: Chr2, 54.46 cM
Alliance: Lmo2tm4Thr page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:59368
Parent Cell Line:  CCB (ES Cell)
Strain of Origin:  129S/SvEv-Gpi1c
Mutation
description
Allele Type:    Targeted (Null/knockout, Reporter)
Mutation:    Insertion
 
Mutation detailsA targeting construct was designed to insert a lacZ-neo into exon 5. Targeted ES cells were targeted a second time with a vector containing a hygromycin resistance gene into the same exon. (J:59368)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Expression
In Mice Carrying this Mutation: 7 assay results
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Lmo2 Mutation:  31 strains or lines available
References
Original:  J:59368 Yamada Y, et al., The oncogenic LIM-only transcription factor Lmo2 regulates angiogenesis but not vasculogenesis in mice. Proc Natl Acad Sci U S A. 2000 Jan 4;97(1):320-4
All:  3 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/09/2024
MGI 6.23
The Jackson Laboratory