Summary | Mutation origin | Mutation description | Phenotypes | Find Mice (IMSR) | References

Symbol:	Lmo2tm3Thr
Name:	LIM domain only 2; targeted mutation 3, Terence H Rabbitts
MGI ID:	MGI:3584019
Synonyms:	Lmo2fl
Gene:	Lmo2  Location: Chr2:103788340-103812223 bp, + strand  Genetic Position: Chr2, 54.46 cM
Alliance:	Lmo2tm3Thr page

Germline Transmission:	Earliest citation of germline transmission: J:86869
Parent Cell Line:	CCB (ES Cell)
Strain of Origin:	129S/SvEv-Gpi1c

Allele Type:    Targeted (Conditional ready, No functional change) Mutation:    Insertion   Mutation details: A set of two targeting vectors were used to insert a loxP-hygro into intron 4 and a puro-loxP into intron 6, to flank the majority of the coding sequence. (J:86869)

View phenotypes and curated references for all genotypes (concatenated display).

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Lmo2 Mutation:	31 strains or lines available

Original:	J:86869 McCormack MP, et al., The LMO2 T-cell oncogene is activated via chromosomal translocations or retroviral insertion during gene therapy but has no mandatory role in normal T-cell development. Mol Cell Biol. 2003 Dec;23(24):9003-13
All:	1 reference(s)