Summary | Mutation origin | Mutation description | Find Mice (IMSR) | References

Symbol:	Fgfr2tm2.1Dsn
Name:	fibroblast growth factor receptor 2; targeted mutation 2.1, Clive Dickson
MGI ID:	MGI:2153814
Synonyms:	FgfR2-IIIcneo-deltaflox
Gene:	Fgfr2  Location: Chr7:129764181-129868538 bp, - strand  Genetic Position: Chr7, 73.19 cM
Alliance:	Fgfr2tm2.1Dsn page

Germline Transmission:	Earliest citation of germline transmission: J:72517
Parent Cell Line:	Not Specified (ES Cell)
Strain of Origin:	129

Allele Type:    Targeted (Null/knockout) Mutation:    Intragenic deletion   Mutation details: This allele is a derivative of Fgfr2tm2Dsn in which the exon 9 sequences were deleted by crossing mice carrying the Fgfr2tm2Dsn allele to mice which expresss Cre recombinase in the germ line. (J:72517)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Fgfr2 Mutation:	87 strains or lines available

Original:	J:72517 Hajihosseini MK, et al., A splicing switch and gain-of-function mutation in FgfR2-IIIc hemizygotes causes Apert/Pfeiffer-syndrome-like phenotypes. Proc Natl Acad Sci U S A. 2001 Mar 27;98(7):3855-60
All:	1 reference(s)