Summary | Mutation origin | Mutation description | Phenotypes | Find Mice (IMSR) | References

Symbol:	Hus1tm1Rsw
Name:	HUS1 checkpoint clamp component; targeted mutation 1, Robert S Weiss
MGI ID:	MGI:3583575
Synonyms:	Hus1flox
Gene:	Hus1  Location: Chr11:8943137-8961191 bp, - strand  Genetic Position: Chr11, 5.74 cM
Alliance:	Hus1tm1Rsw page

Germline Transmission:	Earliest citation of germline transmission: J:99339
Parent Cell Line:	TC1/TC-1 (ES Cell)
Strain of Origin:	129S6/SvEvTac

Allele Type:    Targeted (Conditional ready, No functional change) Mutation:    Insertion   Mutation details: This allele is a child of Hus1tm2Rsw, and resulted from crossing those with mice expressing FLP recombinase in the germline to remove the FRT flanked neomycin resistance cassette. Exons 2 and 3 remained flanked by loxP sites. (J:99339)

View phenotypes and curated references for all genotypes (concatenated display).

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Hus1 Mutation:	20 strains or lines available

Original:	J:99339 Levitt PS, et al., Conditional inactivation of the mouse Hus1 cell cycle checkpoint gene. Genomics. 2005 Aug;86(2):212-24
All:	5 reference(s)