Summary | Mutation origin | Mutation description | Phenotypes | Find Mice (IMSR) | References

Symbol:	Fgfr1tm5.1Jrt
Name:	fibroblast growth factor receptor 1; targeted mutation 5.1, Janet Rossant
MGI ID:	MGI:2153350
Synonyms:	l15
Gene:	Fgfr1  Location: Chr8:26008808-26067819 bp, + strand  Genetic Position: Chr8, 14.12 cM
Alliance:	Fgfr1tm5.1Jrt page

Germline Transmission:	Earliest citation of germline transmission: J:49154
Parent Cell Line:	R1 (ES Cell)
Strain of Origin:	(129X1/SvJ x 129S1/Sv)F1-Kitl+

Allele Type:    Targeted (Null/knockout) Mutation:    Insertion   Mutation details: This allele is a derivative of Fgfr1tm5Jrt in which the loxP flanked neomycin cassette was removed via Cre mediated recombination by crossing Fgfr1tm5Jrt mice with transgenic mice expressing Cre under the control of a CMV or beta-actin promoter. (J:49154)

View phenotypes and curated references for all genotypes (concatenated display).

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Fgfr1 Mutation:	221 strains or lines available

Original:	J:49154 Partanen J, et al., Opposite phenotypes of hypomorphic and Y766 phosphorylation site mutations reveal a function for Fgfr1 in anteroposterior patterning of mouse embryos. Genes Dev. 1998 Aug 1;12(15):2332-44
All:	1 reference(s)