Summary | Mutation origin | Mutation description | Expression | Phenotypes | Find Mice (IMSR) | References

Symbol:	Tnftm1.2Sned
Name:	tumor necrosis factor; targeted mutation 1.2, Sergei A Nedoskasov
MGI ID:	MGI:3576929
Synonyms:	TNFdelta
Gene:	Tnf  Location: Chr17:35418357-35420983 bp, - strand  Genetic Position: Chr17, 18.59 cM
Alliance:	Tnftm1.2Sned page

Germline Transmission:	Earliest citation of germline transmission: J:97783
Parent Cell Line:	Not Specified (ES Cell)
Strain of Origin:	129/Sv

Allele Type:    Targeted (Null/knockout) Mutation:    Intragenic deletion   Mutation details: Exons 3 and 4 were deleted via cre-mediated recombination following the insertion of loxP sites and a floxed neo into intron 2 and the 3' UTR, respectively. (J:97783)

View phenotypes and curated references for all genotypes (concatenated display).

In Structures Affected by this Mutation:

1 anatomical structure(s)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Tnf Mutation:	46 strains or lines available

Original:	J:97783 Kuprash DV, et al., Novel tumor necrosis factor-knockout mice that lack Peyer's patches. Eur J Immunol. 2005 May;35(5):1592-600
All:	7 reference(s)