Summary | Mutation origin | Mutation description | Find Mice (IMSR) | References

Symbol:	Cfl1tm1Wit
Name:	cofilin 1, non-muscle; targeted mutation 1, Walter Witke
MGI ID:	MGI:3574397
Synonyms:	lox/neo-Cof
Gene:	Cfl1  Location: Chr19:5540483-5544059 bp, + strand  Genetic Position: Chr19, 4.34 cM
Alliance:	Cfl1tm1Wit page

Germline Transmission:	Earliest citation of germline transmission: J:96452
Parent Cell Line:	Not Specified (ES Cell)
Strain of Origin:	129

Allele Type:    Targeted (Conditional ready, No functional change) Mutation:    Insertion     A targeting construct was designed to flank exon 2 with a loxP site and a floxed neo. (J:96452)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Cfl1 Mutation:	25 strains or lines available

Original:	J:96452 Gurniak CB, et al., The actin depolymerizing factor n-cofilin is essential for neural tube morphogenesis and neural crest cell migration. Dev Biol. 2005 Feb 1;278(1):231-41
All:	2 reference(s)