Summary | Mutation origin | Mutation description | Expression | Phenotypes | Find Mice (IMSR) | References

Symbol:	Itgb4tm2Son
Name:	integrin beta 4; targeted mutation 2, Arnoud Sonnenberg
MGI ID:	MGI:3573958
Synonyms:	Beta4flox
Gene:	Itgb4  Location: Chr11:115865556-115899238 bp, + strand  Genetic Position: Chr11, 80.91 cM
Alliance:	Itgb4tm2Son page

Germline Transmission:	Earliest citation of germline transmission: J:96543
Parent Cell Line:	Not Specified (ES Cell)
Strain of Origin:	129P2/OlaHsd

Allele Type:    Targeted (Conditional ready, No functional change) Mutation:    Insertion   Mutation details: Exons 1b-5 were left flanked with loxP sites following transient cre expression and the excision of a floxed neo. (J:96543)

View phenotypes and curated references for all genotypes (concatenated display).

In Structures Affected by this Mutation:

1 anatomical structure(s)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Itgb4 Mutation:	107 strains or lines available

Original:	J:96543 Raymond K, et al., Keratinocytes display normal proliferation, survival and differentiation in conditional {beta}4-integrin knockout mice. J Cell Sci. 2005 Mar 1;118(Pt 5):1045-60
All:	12 reference(s)