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Elf5tm1Mapr
Targeted Allele Detail
Nomenclature
Symbol: Elf5tm1Mapr
Name: E74-like factor 5; targeted mutation 1, Melanie A Pritchard
MGI ID: MGI:3573855
Synonyms: Elf5-
Gene: Elf5  Location: Chr2:103411693-103450989 bp, + strand  Genetic Position: Chr2, 54.43 cM, cytoband E3
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:96237
Parent Cell Line:  J1 (ES Cell)
Strain of Origin:  129S4/SvJae
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
 
Mutation detailsPart of exon 3 was replaced with an NLS-LacZ-neo cassette. The construct was designed such that a fusion product containing the first 28 amino acids would be fused to Beta-gal. Northern blot of mutant mammary glands indicated that the null allele did not create any alternatively spliced transcripts. (J:96237)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Elf5 Mutation:  11 strains or lines available
References
Original:  J:96237 Zhou J, et al., Elf5 is essential for early embryogenesis and mammary gland development during pregnancy and lactation. EMBO J. 2005 Feb 9;24(3):635-44
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
06/30/2020
MGI 6.15
The Jackson Laboratory