Summary | Mutation origin | Mutation description | Expression | Phenotypes | Disease models | Find Mice (IMSR) | References

Symbol:	Chd8tm1Kei
Name:	chromodomain helicase DNA binding protein 8; targeted mutation 1, Keiichi I Nakayama
MGI ID:	MGI:3530648
Synonyms:	Chd8deltaSL
Gene:	Chd8  Location: Chr14:52435608-52495237 bp, - strand  Genetic Position: Chr14, 26.84 cM
Alliance:	Chd8tm1Kei page

Germline Transmission:	Earliest citation of germline transmission: J:92968
Parent Cell Line:	E14 (ES Cell)
Strain of Origin:	129P2/OlaHsd

Allele Type:    Targeted (Null/knockout) Mutations:    Insertion, Intragenic deletion     A PGK-lox-neo-polyA cassette replaced all of the exons in the locus. (J:92968)

View phenotypes and curated references for all genotypes (concatenated display).

In Mice Carrying this Mutation:	60 assay results
In Structures Affected by this Mutation:	5 anatomical structure(s)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Chd8 Mutation:	103 strains or lines available

Original:	J:92968 Nishiyama M, et al., Early embryonic death in mice lacking the beta-catenin-binding protein Duplin. Mol Cell Biol. 2004 Oct;24(19):8386-94
All:	6 reference(s)