Summary | Mutation origin | Mutation description | Phenotypes | Find Mice (IMSR) | Notes | References

Symbol:	GsrGt(OST124402)Lex
Name:	glutathione reductase; gene trap OST124402, Lexicon Genetics
MGI ID:	MGI:3530486
Synonyms:	GsrGt(neo)472Lex
Gene:	Gsr  Location: Chr8:34143266-34188190 bp, + strand  Genetic Position: Chr8, 20.69 cM
Alliance:	GsrGt(OST124402)Lex page

Mutant Cell Line:	OST124402
Germline Transmission:	Earliest citation of germline transmission: J:103485
Parent Cell Line:	Lex-1 (ES Cell)
Strain of Origin:	129S5/SvEvBrd
Project Collection:	Lexicon

Allele Type:    Gene trapped (Null/knockout, Reporter) Mutation:    Insertion of gene trap vector   Mutation details: Retroviral insertion occurred in the intron between exons 1 and 2. RT-PCR analysis revealed that the transcript was absent in the homozygous mutant mice. (J:103485) Sequence Tags:  Sequence tag details (1 tag) Tag ID GenBank ID Method Tag Location (trapped strand)* Select OST124402 CG536453 (MGI Seq Detail) 3' RACE Chr8:34159918-34166685 bp (+) * GRCm39 (strand of gene trap mutagenesis) Selected Tags: download BLAST at NCBI Genome Context:  Genome Browser view of this mutation 30 gene trap insertions have trapped this gene View all gene trap sequence tags in this region

View phenotypes and curated references for all genotypes (concatenated display).

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 2 strains available      Cell Lines: 1 line available
Carrying any Gsr Mutation:	51 strains or lines available

Original:	J:103485 Lexicon Genetics Inc, NIH initiative supporting placement of Lexicon Genetics, Inc. mice into public repositories. MGI Direct Data Submission. 2005;
All:	3 reference(s)