Summary | Mutation origin | Mutation description | Expression | Phenotypes | Find Mice (IMSR) | References

Symbol:	Mttptm2Sgy
Name:	microsomal triglyceride transfer protein; targeted mutation 2, Steven G Young
MGI ID:	MGI:2152202
Synonyms:	Mttpfl
Gene:	Mttp  Location: Chr3:137795616-137849179 bp, - strand  Genetic Position: Chr3, 64.06 cM
Alliance:	Mttptm2Sgy page

Germline Transmission:	Earliest citation of germline transmission: J:54612
Parent Cell Line:	J1 (ES Cell)
Strain of Origin:	129S4/SvJae

Allele Type:    Targeted (Conditional ready, No functional change) Mutation:    Insertion   Mutation details: A neomycin resistance cassette flanked by loxP sites was inserted into intron 1. An additional loxP site was inserted 2.5 kb upstream of the promoter and exon 1. (J:54612)

View phenotypes and curated references for all genotypes (concatenated display).

In Structures Affected by this Mutation:

2 anatomical structure(s)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 2 strains available      Cell Lines: 0 lines available
Carrying any Mttp Mutation:	53 strains or lines available

Original:	J:54612 Raabe M, et al., Analysis of the role of microsomal triglyceride transfer protein in the liver of tissue-specific knockout mice. J Clin Invest. 1999 May;103(9):1287-98
All:	41 reference(s)