Summary | Mutation origin | Mutation description | Phenotypes | Find Mice (IMSR) | References

Symbol:	Aldh2Gt(OST7285)Lex
Name:	aldehyde dehydrogenase 2, mitochondrial; gene trap OST7285, Lexicon Genetics
MGI ID:	MGI:3530243
Synonyms:	Aldh2Gt(Betageo)412Lex
Gene:	Aldh2  Location: Chr5:121704090-121731887 bp, - strand  Genetic Position: Chr5, 61.86 cM, cytoband F-G1
Alliance:	Aldh2Gt(OST7285)Lex page

Mutant Cell Line:	OST7285
Germline Transmission:	Earliest citation of germline transmission: J:152060
Parent Cell Line:	Lex-1 (ES Cell)
Strain of Origin:	129S5/SvEvBrd
Project Collection:	Lexicon

Allele Type:    Gene trapped (Null/knockout, Reporter) Mutation:    Insertion of gene trap vector   Mutation details: The gene trap vector inserted into intron 2. Western blot analysis confirmed the absence of protein expression in liver mitochondria. (J:152060) Sequence Tags:  Sequence tag details (1 tag) Tag ID GenBank ID Method Tag Location (trapped strand)* Select OST7285 CG477397 (MGI Seq Detail) 3' RACE Chr5:121714026-121714613 bp (-) * GRCm39 (strand of gene trap mutagenesis) Selected Tags: download BLAST at NCBI Genome Context:  Genome Browser view of this mutation 19 gene trap insertions have trapped this gene View all gene trap sequence tags in this region

View phenotypes and curated references for all genotypes (concatenated display).

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Aldh2 Mutation:	35 strains or lines available

Original:	J:152060 Fernandez E, et al., Monoamine metabolism and behavioral responses to ethanol in mitochondrial aldehyde dehydrogenase knockout mice. Alcohol Clin Exp Res. 2006 Oct;30(10):1650-8
All:	6 reference(s)