Summary | Mutation origin | Mutation description | Phenotypes | Find Mice (IMSR) | Notes | References

Symbol: Rgs11tm1Lex Name: regulator of G-protein signaling 11; targeted mutation 1, Lexicon Genetics MGI ID: MGI:3528953 Gene: Rgs11  Location: Chr17:26421925-26430298 bp, + strand  Genetic Position: Chr17, 13.07 cM Alliance: Rgs11tm1Lex page

Rgs7tm1Cjch/Rgs7tm1Cjch Rgs11tm1Lex/Rgs11tm1Lex mice have no ERG b-waves and contain ultrastructural defects in the retinal outer plexiform layer Show the 1 phenotype image(s) involving this allele.

Germline Transmission:	Earliest citation of germline transmission: J:103485
Parent Cell Line:	Not Specified (ES Cell)
Strain of Origin:	129S5/SvEvBrd
Project Collection:	Lexicon

Allele Type:    Targeted (Null/knockout) Mutation:    Not Specified   Mutation details: Coding exons 1 through 4 were targeted. Gene inactivation was confirmed by a lack of protein detected in immunoblot assays of retinal extracts. (J:103485, J:141120)

View phenotypes and curated references for all genotypes (concatenated display).

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 2 strains available      Cell Lines: 0 lines available
Carrying any Rgs11 Mutation:	31 strains or lines available

Original:	J:103485 Lexicon Genetics Inc, NIH initiative supporting placement of Lexicon Genetics, Inc. mice into public repositories. MGI Direct Data Submission. 2005;
All:	14 reference(s)