Summary | Mutation origin | Mutation description | Expression | Phenotypes | Find Mice (IMSR) | References

Symbol:	Il23atm1Dnax
Name:	interleukin 23, alpha subunit p19; targeted mutation 1, DNAX Research Institute of Cellular and Molecular Biology
MGI ID:	MGI:3527219
Synonyms:	Il-23-, IL23a-, Il23atm1Cua, Il-23p19-, Il23p19tm1Dnax
Gene:	Il23a  Location: Chr10:128132009-128133953 bp, - strand  Genetic Position: Chr10, 76.51 cM, cytoband D3
Alliance:	Il23atm1Dnax page

Germline Transmission:	Earliest citation of germline transmission: J:89968
Parent Cell Line:	Not Specified (ES Cell)
Strain of Origin:	Not Specified

Allele Type:    Targeted (Null/knockout) Mutations:    Insertion, Intragenic deletion   Mutation details: A neo replaced exons 1-4. Quantitative RT-PCR analysis of mutant lymph node tissue demonstrated the complete lack of transcript. (J:89968)

View phenotypes and curated references for all genotypes (concatenated display).

In Mice Carrying this Mutation:

1 RNA-Seq or microarray experiment(s)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Il23a Mutation:	25 strains or lines available

Original:	J:89968 Cua DJ, et al., Interleukin-23 rather than interleukin-12 is the critical cytokine for autoimmune inflammation of the brain. Nature. 2003 Feb 13;421(6924):744-8
All:	59 reference(s)