Summary | Mutation origin | Mutation description | Phenotypes | Find Mice (IMSR) | References

Symbol:	Arr3tm1Chcr
Name:	arrestin 3, retinal; targeted mutation 1, Cheryl M Craft
MGI ID:	MGI:3527130
Synonyms:	Arr4-
Gene:	Arr3  Location: ChrX:99649103-99662099 bp, + strand  Genetic Position: ChrX, 43.72 cM, cytoband C2
Alliance:	Arr3tm1Chcr page

Germline Transmission:	Earliest citation of germline transmission: J:139694
Parent Cell Line:	Not Specified (ES Cell)
Strain of Origin:	129S/SvEv

Allele Type:    Targeted (Null/knockout, Reporter) Mutations:    Insertion, Intragenic deletion   Mutation details: The lacZ/neo cassette was inserted at the 5'end of exon 1 and replaces about 2 kb of the gene sequence including exons 1-5. The absence of protein expression was confirmed by immunohistochemistry on eye sections. (J:139694)

View phenotypes and curated references for all genotypes (concatenated display).

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Arr3 Mutation:	11 strains or lines available

Original:	J:139694 Nikonov SS, et al., Mouse cones require an arrestin for normal inactivation of phototransduction. Neuron. 2008 Aug 14;59(3):462-74
All:	7 reference(s)