Summary | Mutation origin | Mutation description | Expression | Phenotypes | Find Mice (IMSR) | References

Symbol:	Emx2tm1Pgr
Name:	empty spiracles homeobox 2; targeted mutation 1, Peter Gruss
MGI ID:	MGI:2148858
Synonyms:	Emx-, Emx2-, Emx2KO
Gene:	Emx2  Location: Chr19:59447122-59453789 bp, + strand  Genetic Position: Chr19, 56.28 cM
Alliance:	Emx2tm1Pgr page

Germline Transmission:	Earliest citation of germline transmission: J:37631
Parent Cell Line:	R1 (ES Cell)
Strain of Origin:	(129X1/SvJ x 129S1/Sv)F1-Kitl+

Allele Type:    Targeted (Null/knockout) Mutations:    Insertion, Intragenic deletion   Mutation details: A 250 bp PvuII-PvuII fragment in the sequences encoding the 5' part of the homeobox was replaced with a neomycin cassette. (J:37631) Inheritance:    Recessive

View phenotypes and curated references for all genotypes (concatenated display).

In Mice Carrying this Mutation:	214 assay results
In Structures Affected by this Mutation:	13 anatomical structure(s)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Emx2 Mutation:	23 strains or lines available

Original:	J:37631 Pellegrini M, et al., Dentate gyrus formation requires Emx2. Development. 1996 Dec;122(12):3893-8
All:	41 reference(s)