Summary | Mutation origin | Mutation description | Expression | Phenotypes | Find Mice (IMSR) | References

Symbol:	Sod1tm1Ysh
Name:	superoxide dismutase 1, soluble; targeted mutation 1, Ye-Shih Ho
MGI ID:	MGI:3526701
Synonyms:	Sod1-
Gene:	Sod1  Location: Chr16:90017650-90023221 bp, + strand  Genetic Position: Chr16, 51.56 cM, cytoband B5-C3
Alliance:	Sod1tm1Ysh page

Germline Transmission:	Earliest citation of germline transmission: J:46672
Parent Cell Line:	R1 (ES Cell)
Strain of Origin:	(129X1/SvJ x 129S1/Sv)F1-Kitl+

Allele Type:    Targeted (Null/knockout) Mutations:    Insertion, Intragenic deletion   Mutation details: Exon 5 was replaced with a neomycin resistance gene. mRNA could not be detected in the tissues of homozygous mice. (J:46672)

View phenotypes and curated references for all genotypes (concatenated display).

In Structures Affected by this Mutation:

1 anatomical structure(s)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Sod1 Mutation:	37 strains or lines available

Original:	J:46672 Ho YS, et al., Reduced fertility in female mice lacking copper-zinc superoxide dismutase. J Biol Chem. 1998 Mar 27;273(13):7765-9
All:	13 reference(s)