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Maftm1Mym
Targeted Allele Detail
Summary
Symbol: Maftm1Mym
Name: MAF bZIP transcription factor; targeted mutation 1, Masayuki Yamamoto
MGI ID: MGI:2148637
Synonyms: c-maf -
Gene: Maf  Location: Chr8:116429992-116433633 bp, - strand  Genetic Position: Chr8, 62.61 cM
Alliance: Maftm1Mym page
Maftm1Mym/Maftm1Mym mice lack normal lens structure

Show the 1 phenotype image(s) involving this allele.

Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:56095
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  Not Specified
Mutation
description
Allele Type:    Targeted (Null/knockout, Reporter)
Mutations:    Insertion, Intragenic deletion
 
Mutation detailsMost of the coding region was replaced with an in-frame lacZ gene followed by a neomycin cassette. A MAF-beta galactosidase fusion protein is expressed from this allele. (J:56095)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Expression
In Mice Carrying this Mutation: 8 assay results
1 RNA-Seq or microarray experiment(s)
In Structures Affected by this Mutation: 1 anatomical structure(s)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Maf Mutation:  26 strains or lines available
References
Original:  J:56095 Kawauchi S, et al., Regulation of lens fiber cell differentiation by transcription factor c-Maf. J Biol Chem. 1999 Jul 2;274(27):19254-60
All:  10 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/19/2024
MGI 6.23
The Jackson Laboratory